Interactive HIV-Host Genome-to-Genome map

Schematic representation of the HLA class I genes and their amino acids associated with HIV-1 amino acid variants in the region. The association between human amino acids and viral amino acid variations are projected on the HIV-1 proteome. Significant associations (assessed with Bonferroni-correction at 1.7E-8) are indicated by a blue dot. The gp120 part of the HIV-1 proteome was not tested. The colored bar below the plot area shows the positions of the optimally defined CD8+ T cell epitopes by black marks.

The figure highlights the relevant connections when the mouse is hovered over specific elements (HLA amino acid, HIV gene, or epitope).

style="fill:rgb(0,0,0);stroke:none" />